Pokémon Gold and Silver/Cerulean City

'Cerulean City is a seaside city located in northern Kanto. It is situated near a sea inlet to the north, with Saffron City to the south, the Rock Tunnel and Power Plant to the east, and Mt. Moon to the west. It is home to Misty, the Cerulean City Gym Leader.'

Bike Shop
The bike shop here is closed. The owner moved the shop to Goldenrod City in Johto.

Berserk Gene
The "Unknown Dungeon" is gone but near where it used to be you can find a Berserk Gene.

Cerulean Gym
Misty is nowhere to be found until after you fix the problem with the Power Plant, then she can be found to the north on Route 25.