Uncharted 2: Among Thieves/Tree of Life

Elena has been badly injured, but you have no choice except to stop Lazarevic from gaining the power of the Cintamani Stone. The conclusion to the game plays out much differently than what has come before, as the developers eschewed a strategic battle, special platforming maneuvers or puzzle-solving in favor of wild running and gunning. The final showdown pits Drake against an overpowered Lazarevic, where nicely honed FPS skills will come in handy. Ditching the more realistic enemy AI model from the rest of the game, Lazarevic is a standard, "damage him to see successively more powerful incarnations" boss, a familiar archetype from the very beginning of gaming on 8-bit systems.

Save the world
Head down the cliffs to the grotto at the bottom, where you'll find the wellspring of the blue resin, which it turns out is actually an elixir for eternal life. Instead of shooting him in the head before he becomes invincible, Drake will wait until Lazarevic has drank his fill and gained immortality before shooting the incredibly flammable substance and blowing everyone up. It causes a huge explosion, but of course Lazarevic is protected by the magic of the resin, so he will get up and begin hunting you down.

You're in a circular area surrounding the flaming, blue pool of resin that will kill you if you stay in it for more than a second. There are plenty of spots to get cover and places where you'll need to climb up a short ledge to keep moving. There is also a small chasm on one side that you'll need to jump over to pass. All over the grotto are large, glowing resin pods. Lazarevic will chase you down, blasting you with his shotgun. The only way to damage him is to shoot out a resin pod while he's beside it and catch him in the blast. The closer he is, the more damage it will cause. Keep running away from him – backwards, if you can – and shoot pods behind you while running. Don't bother wasting the time to aim with psx: L1, unless you can also hide behind some cover, and grenades are also fairly useless here. If Lazarevic catches up to you, he'll grab you and smack you around. Mash psx: S when indicated and he'll throw you away. This encounter will damage you quite a bit, so if you're not at full health, you might die. You'll also want to avoid sticking around the resin pods yourself for very long, as Lazarevic's shots have a fairly wide spread and you'll take a lot of damage from the resulting explosion.

After causing enough damage, Lazarevic will stumble and a small cut scene will play where he yells at you. This happens three times altogether, and after the first two he'll start throwing grenades behind and in front of you. Obviously you'll want to avoid those, but they don't change your tactics any as you'll still just need to blow up the regenerating resin pods while he's near them. After the grenades, he becomes faster and throws more grenades, and when you finally get wear him down a fourth time, it's all over. This fight will be made easier through repetition as you learn where the good spots to stop and turn around are, and a certain amount of skill or dexterity in quickly acquiring your target while moving.

Back to the girls
During the fight, the whole place was coming down around you, and now that's it's over you'll need to get out of there. You'll find yourself in front of a bridge, so head across it as it crumbles. Your job here is to jump at the correct times to make it over the gaps being created. Toward the end of the bridge, your viewpoint will flip and you'll be running toward the camera, but the same moves apply. When you make it back to your friends, you'll be attacked one final time by a Shambhala guardian, and you'll need to shoot him while sliding down the tilting bridge in an interactive cut scene. That marks the last player-controlled sequence of the game. Continue watching the movies to see what happens with the characters after the dust has settled.