Spyro Orange: The Cortex Conspiracy

Spyro Orange: The Cortex Conspiracy (known as Spyro Fusion in Europe and Spyro Advance: Waku Waku Tomodachi Daisakusen! in Japan) is the fourth Spyro game for the Game Boy Advance. It is one part in a crossover pair between the and  game universes.

Plot
Doctor Neo Cortex, Crash Bandicoot's sworn enemy, has joined forces with Spyro the Dragon's enemy, Ripto, in a plan to get rid of both Spyro and Crash using Ripto's monsters. Aku Aku and Coco ask Crash to recover the crystals to save the world before Cortex does.

Meanwhile, the Professor and Hunter ask Spyro to close the portals and get rid of the monsters. Unfortunately for Crash and Spyro, they were tricked because on Crash's world, the Riptocs are dressed as Spyro and on Spyro's world, they are dressed as Crash.

Crash and Spyro meet and engage in a bridge fight, until they realized they have been tricked. A new friendship bloom between them and they joined forces to defeat the two evil villains.

Not even Tiny Tiger and Crush and Gulp can stop them, but Cortex uses his niece, Nina Cortex, to kidnap Coco and the Professor. Spyro rescues Coco and the Professor while Crash distracts Nina. Finally, Crash and Spyro defeat Nina at her own game.

Coco has an idea, if they put a tracer on Cortex and Ripto, they could track them to their headquarters. Crash and Spyro reach to the headquarters in space. As a team, Crash and Spyro defeat Cortex and Ripto. Then, they thank each other and the game ends when a photo was taken of Crash with Spyro in a friendly headlock.