No More Heroes 2: Desperate Struggle

No More Heroes: Desperate Struggle (ノーモア★ヒーローズ デスパレート ストラグル) is an action video game developed for the Wii, PlayStation 3 and Xbox 360 video game systems as a direct sequeal to No More Heroes. It was directed by Suda51, developed by Grasshopper Manufacture, published by Ubisoft in North America, Rising Star Games in Europe, AFA Interactive in Australia and Marvelous Entertainment in Japan. The game was released on January 26, 2010 for the Wii in North America. A Japanese release date has been set for the PS3 and Xbox 360 versions as February 25, 2010.

Travis Touchdown, the series protagonist, has withdrawn from the ranks of the UAA for three years. During those three years, Travis has fallen to 51st place, and Santa Destroy has been taken over and renovated by the "Pizza Butt" corporation, who in the first game were looking to open restaurants in the town.

Sylvia Christel, the "agent" who convinced Travis to join the UAA, has returned to invite him back into the ranks once more. Motivated not only by Sylvia, Travis is also fighting to avenge the death of someone close to him.