RuneScape/Runes

Air
The air rune is used for strike spells, bolt spells, blast spells, and wave spells as well as Varrock Teleport, Level 2 Enchant, Lumbridge Teleport, Telekinetic Grab, Falador Teleport, Crumble Undead, Camelot Teleport, Saradomin Strike, Claws of Guthix, Flames of Zamorak, and Charge Air Orb.

Examine: One of the 4 basic elemental runes.

Water
The Water Rune is used for lvl-1 enchantment spells, water strike, water bolt, water blast, bind, confuse, curse, weaken, Falador Teleport, bones to bananas, snare, charge water orb, Ardougne Teleport, bones to peaches, lvl-5 enchantment, vulnerability, water wave, Teleport to Ape Atoll, Enfeeble, entangle, stun and teleother to Falador.

Earth
Used for level 2 enchant spells (emerald jewelry). Also obviously used for earth strike, bolt, blast, and wave. It and the water rune are used for weaken, curse, and confuse.

Fire
Used for 3rd level enchant spells (ruby jewelry. Obviously used for fire strike, bolt, blast, and wave.

Mist rune
(Water & Air)

Mud rune
(Water & Earth)

Dust rune
(Earth & Air)

Lava rune
(Earth & Fire)

Smoke rune
(Fire & Air)

Steam rune
(Water & Fire)

Mind rune
This rune is used for basic level missile spells. It can be used in the strike spells. It respawns in Lumbridge Castle and Varrock Sewers. Requires level 2 runecrafting to make.

Examine: Used for basic level missile spells

Body
(low level weakening spells)

Soul
(high level weakening spells and for one teleportation spell)

Nature
The Nature Rune is one of types of Runes in MMORPG RuneScape. It is very useful Rune because it is used to cast spells for changing things.
 * Used for: Alchemy, Binding, and Transformation.

Here is List of spells that use Nature Rune:

Law
Used for teleportation (any teleportation spell, except for tele-other) and for telekinetic grab (telekinesis); worth about 1k if only 1 or 2 are bought, like when a player is out, and they need to go someplace. They are bought 300 each in bulk.

Cosmic
Used for enchanting jewlery (turns an emerald amulet into an amulet of defence, Ruby ammy -> Ammy of strength, sapphire ring -> RIng of recoil, ertc.)).

Astral
(Lunar Spells) This spell set can only be acquired after doing the member's quest called Lunar Diplomacy.