City of Heroes/Scrappers

The idea behind Super Reflexes is very simple: don't get hit. If you don't get hit, then you don't take damage, and you also don't suffer the secondary effects of many attacks, like knockdowns, stuns, etc. Unfortunately, you will still get hit sometimes, and it will hurt. A lot. The SR powerset contains no damage mitigation and no healing. You have high defense, and that's it. You will need to run a lot of toggles, which will draw a lot of endurance, but at the higher levels you can be formidable. No matter how much resistance or healing other scrappers may have, they can still be overwhelmed by hard hitting bad guys. As long as you don't get hit, you can outlast any of them. Of course, sooner or later, you will get hit. SR is a gambler's defense. As long as luck is on your side, nothing can touch you.

Powers
Focused Fighting

Focused Senses

Agile

Practiced Brawler

Dodge

Quickness

Lucky

Evasion

Elude