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Keyboard and mouse mappings can be changed in the options. The Windows version also supports Xbox 360 controllers but note that some functions are only available on the keyboard.

Keyboard and Mouse Xbox 360 PlayStation 3 Wii U Action
PC Mouse.png Neutral rstick Neutral rstick Neutral rstick Look / Aim
WASD /  ↑  ↓  Neutral lstick Neutral lstick Neutral lstick Movement
Space A button Cross button X button Jump
LShift LB button L2 button L button Sprint
C L button L3 button Press lstick Crouch
PC Mouse Right Click.png LT button L1 button ZL button Cover
PC Mouse Left Click.png RT button R1 button ZR button Fire Weapon
R X button Square button A button Reload Weapon
H Y button Triangle button B button Holster / Draw Weapon
PC Mouse Wheel Neutral.png / RShift R button R3 button Press rstick Iron Sight / Scope
G RB button R2 button R button Throw / Detonate Grenade
E X button Square button A button Interact
Q B button Circle button Y button Takedown (tap for non-lethal, hold for lethal)
F1 Up dpad Up dpad Up dpad Activate Cloak
F2 Right dpad Right dpad Right dpad Activate Typhoon
F3 Down dpad Down dpad Down dpad Activate X-Ray Vision
F4 Left dpad Left dpad Left dpad Activate Silent Movement
O N/A N/A GamePad Screen Augmentations
I N/A N/A GamePad Screen Inventory
[ N/A N/A GamePad Screen Mission Logs
M / P N/A N/A GamePad Screen 2D Map
` (Tilde) N/A N/A N/A Toggle Quickbar Auto-Hide
- N/A N/A Hold B button for the weapon wheel Previous Weapon
= N/A N/A Hold B button for the weapon wheel Next Weapon
T N/A N/A A button hold to mark/unmark a person/s Mark & Track
F5 N/A N/A N/A Quick Save
F8 N/A N/A N/A Quick Load
Esc Start button Start button Plus button Pause Menu
Tab Back button Select button GamePad Screen Game Menu / Inventory
N/A N/A N/A GamePad Screen Infologs
1-0 Y hold Triangle hold B hold Quick Inventory

Wii-U addition: You can leave audio messages or text for people online to use which is available on the Gamepad screen during the game. Be prepared, follow the instructions and agree on the Mii online post for this notion to work.