| Item | Selling price | Use | First seen
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| Rope | $25 | In Vault 15, you will need it to descend down the elevator shafts. In the Glow, you'll need to attach the rope to the beam and descend down the crater. | Shady Sands has one in one of the houses in the farm. You can also buy one from Seth.
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| Tool | $200 | Use it whenever you are repairing things to get an increase of 25% to the 'Repair' skill. | You start out with one if you have enough repair skill. Killian has one in his store.
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| Lockpicks | $150 | Use it whenever you are picking conventional locks for an increase to the 'Lockpick' skill. | You start out with them, or you can get them from the fridge in the Raiders base.
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| Electronic Lockpicks | $375 | Use it whenever you are picking electronic locks for an increase in the 'Lockpick' skill. | You must give the necklace that Hightower owns to Loxley. He'll send you to Jasmine, who will give you a set of electronic lockpicks.
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| Radio | $350 | Use it to draw off the mutants in the military base, and it can also be used to remotely toggle the computer in the base. | I traded some caps and flares for it from Lars at Junktown.
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| Flares | $35 | Twist the cap and drop the flare for an increase in brightness in an area. Not too great. | You start out with them.
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| Dynamite | $500 | Set the timer and the explosives will blow. Good for destroying forcefields, disabling locks on locked doors, and killing immobile foes (i.e, Master). | Vault 15 lockers, third floor
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| Plastic Explosives | $850 | Same as Dynamite, but a bit more powerful. | Tyne sells it. He is a merchant in Adytum; to get to his store, head on to the left and enter the small shack and descend down the ladder. Or if you've visited the Military Base, some pieces are in a locker in the fourth floor.
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| First Aid Kit | $200 | Increases 'First Aid' skill if you use this item. | You start out with one.
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| Doctor's Bag | $300 | Increases 'Doctor' skill if you use this item. | There is one in Razlo's bookcase.
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| Motion Sensor for Pip-Boy | $800 | Lets you see all of the critters on the Pip-Boy automap. | Random encounter (police box) or buy from the Hub.
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| Geiger Counter | $650 | Lets you see how much radiation is in your system. | Killian has one.
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| Stealth-Boy | $1800 | Makes you slightly invisible and increases chances using the 'Sneak' skill. | Random encounter (footprint) or kill the Nightkin at the Cathedral.
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| Vats Control Computer Key | $40 | Operates the Vats Control Computer at the Military Base. | The Cathedral tech standing by the Vats Control Computer has one.
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| Military Base Key | $25 | Arms the nuclear bomb at the Cathedral. | It's in the locker where the lieutenant is nearby.
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| Tape Recorder | $80 | Records Gizmo's confession for Killian so that he has evidence to kill him.
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| Wire Tap (Bug) | $50 | You can plant it on Gizmo's desk to give Killian the evidence | He needs to kill Gizmo.
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| Backpacks, Bags | Less than $100 | It holds items. It's there to better organize your inventory at the expense of carrying weight. | ???
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| Systolic Motivator | $150 | It's required to repair the Power Armor suit on Level 3 of the Brotherhood of Steel. | ???
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| Psychic Nullifier | $1000 | Use it to "nullify" the Master's psychic attacks. | ???
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Holodisks can sell for an average of $100 and can be read with the Pip-Boy. They give out information on various subjects.
| Holodisk name | Selling price | Use | First seen
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| Vault Locations | 100 | Contains information on specific subject. | Mrs. Stapleton has this disc.
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| Mutant transmissions | 100 | Contains information on specific subject. | The dying mutant has this disc.
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| Ancient Brotherhood tape | 100 | Contains information on specific subject. | The dead paladin has one in the Glow.
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| Alpha/Delta/other holodiscs | 100 | Contains information on specific subject. | Get them from the Glow.
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| Mutant autopsies | 100 | Contains information on specific subject. | Vree has this disc. She has two copies of it.
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| Brotherhood history | 100 | Contains information on specific subject. | Sophia has this disc.
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| Maxson's Log | 100 | Contains information on specific subject. | Maxson has this disc.
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| Combination key for Military Base | 100 | Contains information on specific subject. | The nightkin watching the entrance to the Military Base has it.
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| Zimmerman's son's death | 100 | Contains information on specific subject. | Razor has this holodisc.
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Most of the keys are a type of key card instead of a traditional metal key.
| Item | Selling price | Use | First seen
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| Yellow Key Card | 40 | Open the elevators at the Glow. | Level 1, Brotherhood soldier
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| Red Key Card | 10 | Open the elevators at the Glow. | Level 2, dead soldier with remains of a radioactive rat.
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| Blue Key Card | 10 | Open the elevators at the Glow. | Level 4, only dead body
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| Red Pass Key | 12 | Open the locked doors on the first floor of the Cathedral. | Lasher has one. You can barter them from Ton and Sister Francis.
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| Black Pass Key | 400 | Open the locked doors on the first floor of the Cathedral. | Morpheus has one.
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