| Picture
| Name | Description |  |
| | Enlightened Guitarist | Gold Star 20 songs on Expert. | 30
|
| | Hendrix Reborn | Complete Career Lefty and Righty. | 10
|
| | Who Needs the Power | 200k on Cult of Personality without Star Power. | 15
|
| | Whammy Mania | Use the Whammy Bar on every held note on Number of the Beast. | 15
|
| | Star Mania | Activate Star Power 3 times on Through the Fire and Flames on Expert. | 15
|
| | Life of the Party | Host Ranked Online matches and win 15 consecutive songs. | 10
|
| | Search and Destroy | Join Ranked Online matches and win 15 consecutive songs. | 10
|
| | Too Many to Count | Hit 250,000 notes in Career. | 25
|
| | Never Gonna Spend It All | Earn $350,000 in career lifetime earnings. | 10
|
| | That's What Friends Are For | Complete Co-op Career. | 25
|
| | Back Up Hero | Complete all songs as the back-up guitar player. | 10
|
| | Guitar Wizard | Complete all Co-op as the lead guitarist. | 10
|
| | 100 Million!?! Gulp!?! | Earn 100,000,000 points total in Career. | 30
|
| | Streaker | Earn a 150 note streak in a Ranked Online Battle mode match. | 10
|
| | Tone Deaf | Beat any song on the expert difficulty with the games sound options turned down to zero. | 5
|
| | Easy Rider | Complete a Career on the Easy Difficulty. | 5
|
| | Medium Rare | Complete Career Mode on the Medium difficulty. | 10
|
| | Always Hard | Complete Career on the Hard difficulty. | 15
|
| | Solo Career | Complete all Career difficulties. | 25
|
| | Button Masher | Win 15 consecutive Ranked songs online using a standard controller. | 5
|
| | Buy a Guitar Already | Play through a career on the Hard or Expert difficulty using a standard controller. | 15
|
| | Big 'Ol Pile of Wins | Win 500 Online Ranked matches. | 20
|
| | The Long Road Ahead | Complete all difficulties in Career, buy everything from the shop and complete 100 online matches. | 100
|
| | Meet Your Maker | Beat one of the creators of Guitar Hero 3 at their own game. | 20
|
| | Right Hand of God | Complete Career Mode on the Expert difficulty. | 20
|
| | Bronze Streaker | Earn a 100 note Streak in Career or Quick Play. | 5
|
| | Silver Streaker | Earn a 250 note streak in Career or Quick Play. | 10
|
| | Gold Streaker | Earn a 500 note streak in Career or Quick Play. | 15
|
| | Streak Master | Earn a 1000 note streak in Career or Quick Play. | 20
|
| | First Big Score | Score 250,000 on a song. | 5
|
| | Half a Mill' | Score 500,000 on a song. | 10
|
| | Now That's Impressive | Score 750,000 on a song. | 20
|
| | Axe Grinder | Earn 5 stars on all songs on the Easy difficulty. | 10
|
| | Rock Guru | Earn 5 stars on all songs on the Medium difficulty. | 20
|
| | Shredder | Earn 5 stars on all songs on the Hard difficulty. | 30
|
| | Guitar Hero | Earn 5 stars on all songs on the Expert difficulty. | 75
|
| | Perfectionist | 100% a song. | 10
|
| | Ready to Rock | Complete the tutorial. | 5
|
| | Axe Collector | Buy all the Guitars from the shop. | 5
|
| | Track Master | Buy all songs from the shop. | 5
|
| | Got 'em All | Buy all characters from the shop. | 5
|
| | A Couple of Streakers | Earn a 200 note streak in a Co-op match. | 5
|
| | Two Timer | Earn a 500 note streak in a Co-op match. | 10
|
| | Dynamic Duo | Earn a 1000 note streak in a Co-op match. | 15
|
| | Streak Masters | Earn a 2000 note streak in a Co-op match. | 20
|
| | Millionaire Club | Score 1,000,000 on any song in a Co-op match. | 20
|
| | Higher Than Most | Score 700,000 on any song in a Co-op match. | 20
|
| | Easy Duo | Earn 5 stars on all Co-op songs for the Easy difficulty. | 10
|
| | Medium Duo | Earn 5 stars on all Co-op songs for the Medium difficulty. | 20
|
| | Hard Duo | Earn 5 stars on all Co-op songs on the Hard difficulty. | 30
|
| | Living Legends | 5 Star all Co-op songs on Expert. | 75
|
| | Leaders of the Pack | 100% a song in a Co-op match. | 10
|
| | Two by Four | Get an 8X multiplier in a Co-op game. | 5
|
| | Half Mill' Club | Score 500,000 on any song in a Co-op match. | 10
|
| | Burnin' a Hole in Your Pocket | Buy everything from the store. | 10
|
| | The Inhuman Achievement | Complete Through the Fire and Flames on Expert. | 15
|
.
