Note that all of Axl's weapons can rapid-fire and be aimed in any of eight directions; however, he can't move while firing. None of his weapons use any weapon energy, only his transformations do.
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Axl's default weapon, which is available from the start of the game. Every eighth shot or so is a Guard Break.
Press the Special Weapon button while Axl Bullet is equipped to fire the Copy Shot. Destroy a copyable enemy with it and he'll leave behind a DNA Core. Grab the DNA Core to enable the A-Trans weapon.
Enabled when you pick up a DNA Core from a defeated enemy. With this equipped, press the Fire button to transform into the enemy you got the Core from. Press the Character Change button to change back. Axl burns weapon energy while transformed.
This has a very high rapid-fire rate and resembles a laser when fired continuously in one direction.
This has a low firing rate, but its bullets are very powerful and can pass through walls and enemies.
Its shots home in on enemies.
This projects an electrical field in front of it. It has a short range, but a wide angle, and it's a Guard Break.
It's a flamethrower. 'Nuff said.
Shoots ice bullets that can freeze enemies.
Its shots bounce off walls, floors, and ceilings.
This fires time-delayed grenades which explode on contact with an enemy, or after a couple of seconds. The explosions are Guard Breaks.