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Silver Cave is where you will battle the Legendary Trainer Red who became Pokémon League Champion of Kanto nearly three years ago (he was the protagonist controlled by the player in Pokemon Red, Blue, and Yellow). Don't expect it to be a breeze though, as he is the most powerful trainer in all of Kanto (until you defeat him, of course). His Pokémon are tough, but bring plenty of Revives and Hyper Potions. It may be a good idea to have all your Pokémon levels 70-80, but, with type advantages, it's possible with low level Pokémon too (levels 40-65). If you have a level disadvantage, it's a good idea to have moves which do a fixed amount of damage regardless of stats like Dream Eater, Sandstorm, Sonicboom, etc.
Pikachu will be easy if you have Rock or Ground-type Pokémon. Espeon is weak to Bug, Ghost or other Dark-types. Blastoise just screams for a Grass or Electric-type, but Blastoise has Blizzard in his move set so be careful when using a Grass type. Thunder backed up with a high Special Attack can down him in one hit. Charizard is weak to Rock, Electric and Water. Red's level 75 Snorlax is a tank. Not only can he take an incredible amount of hits, he can regain health with Rest, and then use Snore while still asleep. Use a Fighting Pokémon for best results. A couple of good moves for Snorlax are Dynamic Punch or Rollout, which does increasing damage for successive hits. Venusaur can be downed easily with a Psychic, Flying, Fire or Ice-type. Just figure out a good team that can take advantage of Red's Pokémon types, and be sure that your team is all Level 55-70 and you can defeat Red with barely a scratch.
After Red is defeated, he remains silent and leaves you alone in the cave. Then the end credits will roll. To fight Red again you have to defeat the Elite Four first.