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The game has a hotkey system built in which is dependent on the F1 to F12 keyboard keys. However it also makes use of other keyboard keys such as:

Shortcut	Command
Alt + S	Skill Table
Alt + M	World Map
Alt + O	Options
Alt + P	Party List
Alt + Q	Quest List
Alt + R	Creature Box
Alt + F	Friend List
Alt + T	Control Window
Alt + Z	System Window (includes log out)
Alt + '	Inventory
Alt + I	Inventory
Alt + Space	Inventory
Alt + Ctrl + F4	Quit Game
Ctrl + F	Target Window
Ctrl + H	Main Interface & Hide Item Name
F1 - F12	Quick Slots (Custom Hot Keys)