The Garage[edit]
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At the start of 2-1, Chris and Sheva are in a large room that is devoid of threats. Two hummers are parked in the back. This room contains several treasures, including a BSAA emblem, but should be quickly bypassed during a speed run.
The first section of Chapter 2-1 is great because it lacks an introduction cinematic or cutscene. This means that it loads more quickly than other chapters. As such, its is a prime candidate for efforts such as acquiring unlimited funds and duplicating trade-able items.
Behind the starting point, behind the hummers, and to the left is a barrel that contains a random drop (usually ammo or ₦100). From the barrel, turn to your left and climb up the ladder. Run to the end and jump across. Shoot the BSAA emblem on the wall for 4/30. Walk along the box to the far wall and open the treasure chest for ₦1,000.
Forward and to the left of the starting point is a box with a silver gun case resting on top. It contains a H&K MP5, which should be your fourth weapon and second Machine Gun. This non-upgraded gun can be sold for ₦480.
Next to the exit (the red door in the corner) are two more destructible objects that drop random items (usually ammo or ₦100).
Storage Facility[edit]
Go between the large crates and shoot the laser. Go to the left and shoot another trap. Smash the crates for the ammo or gold. Go back to where you were at the start and this time, choose the other direction. Walk into the crate past the trap and you'll find a green herb. Now turn back and shoot the trap. This is when you'll be ambushed by infected dogs. Go right and shoot the trap. Follow the path and you'll be attacked. After taking care of him, climb up the ladder and go through the crate with missing front and back walls. Jump down and you'll be attacked by shooting Majini (including a larger one) and more dogs. The large one isn't as much of a threat as the dogs and the shooting Majini up on top of the crates (oil tanks will be a target of theirs, making it dangerous for you to get anywhere near them) so focus on them first. Climb up the ladder, claim the gold, and move on forward to the door. Work with your partner to get it open and jump across the bridge to trigger an attack.
Bridge and Sewers[edit]
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A Majini driving a truck will come up fast. Take your chance to shoot the oil drums on either side of the truck. This will tilt the truck over. After the truck is out of the way, more Majini with long bows will come along. Shoot the gas tanks near them and this should net you an achievement/trophy. and go past them to obtain more riches. Afterward, go left and down the stairs. Here should be a tunnel that will lead you into the sewers.
Follow the path and you'll be ambushed by two groups of dogs. When you reach the end, climb up the ladder and team up to open a door. Turn around for a sapphire, and turn forward to trigger an ambush - this time with flying infected. Shoot them all down and travel into the sewers once more. When you get out, you'll reach a marketplace.
Marketplace and Docks[edit]
Shoot the lock off of the green door of a building. Go in and look up to see a dead man with a Port Key. Pick it up and go straight through the green door to unlock the port door. Be weary of the next Majini ambush. Head onto the docks and on the next boat, where a Majini will be waiting for you. Shoot him and walk on past to more docks. Follow the path and climb up back onto previously unreachable land.
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Go straight ahead and jump over the barrier ahead. A cutscene will follow in which HQ sends back-up to your position; Kirk will be shooting from a copter. First, climb onto the building on the right and you'll see a building across from it labeled "Stores Stores Stores". Here will be a BSAA emblem. Shoot it and then continue on forward into the building up ahead with the red doors. After collecting the treasures here, go to the left and you'll see a door that you and your partner can open. Go through it and Kirk will notify you that you're almost at the station.
Follow the path and shoot the three Majini that come to attack in the building. Move out of the building through the door and follow the path upward. Here you'll see a ladder and a cutscene. Here, your back-up will be attacked by the flying B.O.W.s. Kirk will crash and you'll be on your own from here. Shoot them down and move on to the ambush at the door. After you finish killing the Majini, go left and you'll see a bathroom area where another Majini will be waiting for you. Kill him and take the gold. Now go forward and up the stairs (a Majini will be waiting at each staircase). After going all the way up, perform the assist jump. This next part depends on your point of view. If you're playing as Chris, provide Sheva assistance (most preferably with explosives or a rifle) and help her fight the ambush. If you're playing as Sheva, watch out for the attack and go down the stairs. When you go down every staircase and reach a doorway, unlock the door Chris is behind and let him free.
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This next boss will be tough without any sort of explosives. It'll be dangerous to stay close to him with a normal gun without infinite ammo or a grenade/rocket launcher. Run through the streets and he'll chase after you. Shoot the oil drums when he gets near one, but don't stay too close to them yourself. There should be enough oil drums to get him down, but if you happen to run out, grenades are always the best alternative. Pick up the key after he's dead and go through the door he came from. Collect the treasure from the chest and open the door together. Go into the building here and pick up the green herb. Leave the building and move onto the path. Open the door with your partner and a QTE will follow. Perform the necessary button sequences and Delta Team will help out with the situation, putting an end to the chapter.