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The player starts the game with the Turtles in a burning building. Their objective is to rescue April O'Neil from the fire and bring her to safety. The Turtles encounter Foot Soldiers from both sides of the hallway. Some Purple Foot Soldiers appear by breaking down doors, while others come out from the elevator. The trap that the Turtles must avoid are the big cannon balls that fall down the stairs. They will lose some energy if they get hit. With four players playing, the Turtles must watch out for flames falling from the ceiling (unlike a solo player encountering the cannon ball trap only). At the entrance to April's room, the Turtles fight a few Roadkill Rodneys before entering (the character automatically enters April's room upon hearing her scream). In the room, the Turtles battle some more Foot Soldiers including the Orange ones with machine guns and white Foot Soldiers with katanas. A module (drill like machine) appears in the room with Rocksteady inside. Rocksteady starts by saying “Say your prayers, toitles” and then attacks the Turtles by shooting bullets from his machine gun at them in all directions including the air. He also kicks the Turtles from up close and also body checks the Turtles (that's when he puts away his gun and charges across the room). After Rocksteady is defeated, Shredder appears, kidnaps April, and escapes by jumping out of a window laughing. The Turtles follow them.