Simplified to the highest degree, WarioWare: Touched! is collection of 180, five second minigames, thrown at you over and over. The games are usually explained by one or two word instructions. There is a very short intermission between each game that displays the amount of lives you have left, and the current number of minigames that you've gone through. The games are usually based on reflexes and timing through the use of every Nintendo DS (excluding the D-Pad, face buttons, and shoulder buttons).
The controls for WarioWare: Touched! are about as simple as can be. You will never use the D-Pad, face buttons, or shoulder buttons (except when you want to pause the game, and for a few toys).
Some games also use the microphone.