Dead Rising/Saint

In order to acquire the Saint achievement Frank must rescue at least 50 survivors in a single playthrough of 72 Hour Mode.

The most survivors possible Frank can save is 53 of the 54 survivors. Frank can NEVER save all 54. Either Dr Barnaby or Simone Ravendark must die.

This is one of the most challenging of the achievements. However, in order to get 50, you must fail the cases in the game, and I'll explain why. There are only 47 survivors that you can rescue in the mall. The other survivors must be Brad, Frank, Otis, Jessie, Ed and Dr Barnaby. To save them, you must fail case 6-1, then finish all other scoops. If you complete the cases, certain fates await Brad, Jessie, Dr Barnaby and Ed so fail case 6-1 to get "Saint". With that in mind, it does mean you can miss three survivors in the tight schedule and still complete the achievement. To have Dr. Barnaby live, do not meet with Isabella after fighting her or avoid the fight completely and let the story end there.

It is possible to get the proper ending (A) and get saint, rescue every survivor possible in the mall and that should be 47,Otis is also safe which counts for 48, and once you complete Overtime mode,Isabella and Frank are counted as safe and that equals 50 survivors which then equals 20G