The cutscene begins in the open sea during the storm. Jill Valentine with now long hair since Resident Evil 3: Nemesis and now has a new partner driving the boat: Parker Luciana. As Jill is holding a pistol, Parker calls out a large ship on the horizon. Using a rope gadget, they zipped up the rope and thus begins the mission.
First time on the ship[edit]
First off, you get to control Jill but you can't control Parker (unless you're either in Mercenaries or Raid Mode). Anyway, move through the outside of the large ship until you reach a locked door. Aim and shoot the chained lock then go inside. Secondly as a no brainer, you have to go through several rooms until you find a room with the grate on the floor. Along the way, check for herbs and ammo, including the lockers as well.
Tutorial on the ship[edit]
When you reach the room with the metal grate, another cutscene kicks in. While Parker holds the grate up, Jill pulls the gun out but behind her with the color cloaked in red through the eyes of an unknown being. When Jill turns around, she and Parker were surprised by the zombie which looks like a mushy looking monster with its tongue sticking out. Try to shoot as many times as you can depending on the difficulty. Also if by chance the monster froze in pain, that's when you can use the action button which causes Jill to punch that unusual zombie on the head. Once that ends, there will be a cutscene that the mystery has just begun but this is the prologue.
Beach monster slug investigation[edit]
After a major cutscene with the news reporter who gives the background on what used to be a city, then it switches to Jill, Parker and the chief Clive O'Brian. On the first one, scan the one in the middle, following the tutorial. There will be a mysterious chemical inside the monster slug. You'll need to use the Genesis frequently to scan not just monsters for health bonus, but also hidden handprints as well.
It's pretty basic: just scan the monster slugs while collecting ammo around you. Watch out for the first one that suddenly moves. Be thankful it's not too scary as you and Parker were forced to shoot it until it no longer moves. Also note the wooden boathouse next to the tunnel. Watch out for one sample that might explode on you. Once you reach a total of one hundred percent, that's the time to go back to where Brian is. But the monster slug breaks the boathouse. So shoot the final monster then go to Brian to get another cutscene.
Just when you thought it's over, Brian gets a call and commands Jill and Parker to investigate a giant ship Queen Zenobia out at see. This marks the end of Episode 1.