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< Trauma Center: Second Opinion
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The following guide will show you the objectives and some strategies to complete all the episodes in Trauma Center: Second Opinion. Separate strategies are also available for the Hard difficulty. There will be no spoilers in this guide.

Difficulties[edit]

As you increase the difficulty from Easy to Normal to Hard, the following things will happen:

  • Stabilizer recovers less to vitals
  • S Rank requirements are harder
  • XS Rank is available (Hard mode only)
  • Untreated wounds drop vitals faster
  • Some strains of GUILT have more enemies
  • Healing Touch has a lower duration
  • Mistakes deal more damage to vitals
  • Injecting liquids with the syringe takes more time