|Preceded by||Picross e3|
|Followed by||Picross e5|
|Twitch||Picross e4 Channel|
|YouTube Gaming||Picross e4 Channel|
Picross e4 is the fourth game in the Picross e series for the Nintendo 3DS. It features over 150 new puzzles including 20 × 15 puzzles, Micross from Picross e2, and Mega Picross from Picross e3. Additional special puzzles can be unlocked with save data from Picross e, e2, and e3.