A sci-fi city where technology is at an all time high, but instead of using it to be benificial to the population, use it in in the complete opposite. the city is normally dirty, trash thrown about the sidewalk and the skyline packed with skyscrapers and the occasional police force does there rounds.
Even if you try to make a research center city you'll end in a cyber punk city. You can go by three ways: expanding a knowledge city towards prosperity and governmental sector, getting a high-tech iron fist for your corporate town, or unleashing the science and free market on your Orwellian city. Of all types, the cyber punk city is the hardest to make as one city rather than three or two cities stuck together. Also if you make productivity buildings, with time they will become really cool looking, with all that neon and publicity over their bleak walls.