Catch up to R.H.I.N.O. and he and Spider-Man will engage in battle. At first, all you have to do is dodge R.H.I.N.O. while he charges at you and continue moving on to the right until you see a fuel tank against the wall. Jump up and stick to the wall (just under the barbed wire). R.H.I.N.O. will charge at it 3 times opening up a new area. Here you must save two people. Start by pushing the pillar, then grabbing them and taking them outside of the action. Now you have the chance to take down R.H.I.N.O., switch your special to wrecking ball, and keep your distance. This will make him charge at you. Now dodge his charge and hit him in the back until you get your special. Again dodge the charge, then use your special to do significant damage. Continue dodging and attacking in this pattern and you will win easily.