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- This guide is for the 1987 arcade version. For 2007 remake, see Alien Syndrome (2007).
Alien Syndrome is a run and gun arcade game developed by Sega in 1987. Template:Continue Nav Two players control two soldiers named Ricky and Mary, who must fight their way through large eight-way scrolling levels rescuing their comrades who are being held by aliens. After they have rescued a certain number of hostages the exit opens and they can pass through it in order to fight the end-of-level guardian. If this monstrosity is defeated, they move onto the next stage. As well as two player simultaneous gameplay, Alien Syndrome features pick-ups which assist the player including better weapons and maps of the current level.