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World 5-1[edit]

Bio Miracle map stage 5-1a.png
  • You've enter a world made of school objects and utilities. The major new feature of this world is the conveyor belts. They may be directed to the left or right, and they even affect Upa's speed when he jumps up and hits the underside of them. In addition to the belts, there are two new enemies to watch out for, including bombing pencils and winged bags that can't be inflated.
  • Right when you begin, you'll have to contend with a conveyor belt heading to the left. There are a few octopuses on the belt. If you can, inflate the first one, and hit it into the next two. The next belt has three blue dolls to watch out for. The first item box beneath the short conveyor belt heading right contains an hourglass, but it may be more trouble to reach than it's worth. Jump to the small block platform and quickly hop off before it fall. Hit the second item box to obtain a heart.
  • Below the item box with the heart, you'll encounter your first pencil bomber. When he stops flying forward, watch out for the bombs he tosses ahead of himself. Cross the conveyor belt below the wall of erasers, and take the first opportunity to inflate an enemy and ride it to the belt above. More pencil bombers will approach you while you're on the belt, so be patient and wait for them to start flying again.
  • Hop on to the columns of blue paint, and jump to the platform that rises and falls. When you reach it, a group of winged bags will fly on to the screen. They fly until they reach you, and then crash down to the floor. You can't rattle them, so all you can do is trick them into falling early. If you're on the platform and they get close to you, jump up through the top of the screen to advance to the next section before they reach you.
Bio Miracle map stage 5-1b.png
  • Head to the right and collect the milk bottle from the item box if you need some health. Then watch out for another group of winged bags that fly your way. Trick them into dropping early, and then approach the rising platform to your right. After you jump across all three rising platforms, you can choose to jump to the high conveyor belt, or head down to the smaller platform with an item box. The item box contains a jar of milk, but a pencil bomber will appear and attack Upa.
World 5-1 boss
  • Whether you take the high road or the low road, you're going to need some help crossing the gap where a ruler is pointing down from the ceiling. Wait for a flying blue doll to appear, and rattle him to create a platform that you can ride to the next section. Once you arrive safely on the platform, it's a short distance to the end of the stage.
  • Boss: As usual, a large pink pig serves as the boss for this stage. What's unusual is the layout, and the inclusion of conveyor belts on the screen. The pig walks along the bottom level which partly includes a belt going left. Just above him is a short belt heading right. You can use the short belt for safety, but little else. It's best to stand to the pig's right and send enemies flying into him to the left. Just three enemy hits are needed to take the pig down.

World 5-2[edit]

Bio Miracle map stage 5-2a.png
  • Right from the beginning, this stage starts off with a group of flying bags that try to crash down on you from above. On the first conveyor belt, hit the first enemy and send it crashing into the enemies beyond to create a safe passage for yourself. Jump over the solid platform that you come to, as it will begin to drop as soon as you are entirely on it.
  • Throughout the next portion of the stage, you will have to be on the lookout for more dive-bombing bags as they fly overhead. Jump over the gaps and barriers to keep moving at a steady clip and watch out for an other enemies that get in your way while you advance to the right.
  • When you see two pencil bombers attack you while you're on a small platform made of erasers, wait for them to disappear. Winged blue dolls will come to your rescue and help you cross the gap to the next platform beyond. Be very careful when crossing the block bridge, as the middle will fall out from under you. If it does, be prepared to jump to the conveyor to the right before you drop through the bottom.
Bio Miracle map stage 5-2b.png
  • You'll definitely want to stay on the highest platforms beyond the bridge, as they will lead you to an item box containing a valuable heart. Collect it if you can before moving on. Following this platform, a group of pencil bombers will appear. Either crawl under the arc of their bombs, or wait for them to finish throwing before advancing.
World 5-2 boss
  • From here, you should stay along the bottom of the stage. The ceiling opens up for the possibility of flying through it, but you definitely do not want to do that. If you do, you'll find yourself back at the start of the level! Play it safe and keep to the bottom of the stage until the ceiling is closed. Beyond this, there are only a few more winged bags and some short conveyor belts before you reach the boss.
  • Boss: This stage's boss fight will be similar to the last: a large pig with conveyor belts. What makes it harder is that the conveyor belts are on the floor well below the platform that the pig walks on. If you're not careful, you may slide off one of the belts and fall through the bottom of the screen. While any platforms on the bottom are safe, you're still best off in the lower right corner where you can sit on a block that doesn't move, and wait for red dolls to bounce your way. Strike the dolls and ride the last one up in order to push the doll above into the pig. Hit him three times to defeat the boss.

World 5-3[edit]

Bio Miracle map stage 5-3a.png
  • This is a swimming level, similar to 2-3. However, it scrolls horizontally like most other levels. There are few decisions to make, and even fewer item boxes to support you. You must simply swim through the area, watching out for seahorses as you pass from one gap in the wall to the next.
  • The biggest opportunity to collect items comes near the middle of the stage. There are six boxes in a section where the current in the water pushes you to the left. You can't obtain all six boxes. At best, you can get five, the four on the extreme edges, and only one of the middle boxes. Choose the bottom level to obtain a heart instead of the jar of milk from the top level. Be sure to grab the hourglass from the upper right box before continuing on. This will freeze many of the seahorses in place, allowing you to pass safely beyond them.
Bio Miracle map stage 5-3b.png
  • The last opportunity to obtain an item comes along the bottom of the screen. You'll see an item box near the bottom, and you'll have to swim just above the edge of the screen to reach it. It contains a milk jar which will restore any lost health before you reach the boss.
  • As you make your way through the final region, the top and the bottom of the stage are lined with "sharp" pencils. You'll have to carefully navigate your way through the water so as to minimize your contact with these damaging pencil points. Seahorses will continue to attack. It's a good idea to rattle them and wait until they float away before continuing on. That way you don't accidentally push them and risk taking damage when they come flying back. Swim up through the gap in the ceiling at the end to reach the boss.
World 5-3 boss
  • Boss: You are now presented with a brand new boss, a gigantic seahorse. Although the boss is unique, the method of defeating her is the same as always: rattle enemies to inflate them and push them into the giant seahorse. The giant seahorse spits out two regular sized "baby" seahorses periodically. Use them as your weapons against the boss. The difficult part of this fight is staying safe and out of harm's way. The giant seahorse continues to advance towards Upa from one end of the room to the other unless Upa swims to her opposite side. Finding the best time to cross over can be tricky. When swimming from the left side to the right side, it's safe and fastest to swim under the conveyor belt, as it will speed you along to the other side. Going from right to left can be a little trickier. You can hang out below the conveyor belt until the seahorse is beyond you, and then swim above the belt when it's safe to rise. You can also attempt to swim under or over the boss while she's spitting out babies, but watch out for the pencils at the top of the screen. Hit the boss five times to make the usual two treasure chests appear from the ceiling.