After the intro, you'll be plunged directly into a fight. En medias res indeed. No bones about it, though (ha!), this is a very easy fight. Genya Arikado graces you with a Knife. Smack the Skeleton twice with it to gain his soul. After a short explanation on how to use the soul, an Armor Knight teleports in. Use your newfound soul (Up + Y, if you're confused) twice to take him out (should he launch his spear, simply jump over it). You'll be treated to a short explanation on hos to use Guardian souls. Now a Golem will appear! As with the last foe, use your newfound soul to help - throw bones at the Golem, and when he gets near, press and hold R to activate the Armor Knight soul to help save your soul. You'll then get the Golem soul (later on, you'll wish the souls came this easily; for now, they've got the neighborhood tricycle feel, if you know what I mean). The explanation ensues, followed by a little more exposition. The end result is that Ms. Fortner has a very annoying laugh.
Some more story occurs (note the map on the top screen) - and just as a side note, poor Hammer looks so dejected when you tell him Yoko's not coming! Now would be a good time to tell you what conditions you're in now. Right now, you've got no equipment aside from the Knife Arikado gave you, your clothes, and the souls you just received. You have three Potions, and there are some pretty sweet terms in the Library in the menu. Other than that? Nothing. Good luck! Head right to get to... the lost village.