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The numbers in each cell indicate the damage inflicted by the weapons (on top) to the bosses (on the left). For the Mega Buster, the first number represents the damage inflicted by a normal shot and the second number the damage by a charged one. The green indicates the weapon(s) that deal the most damage.
| Robot Masters | Mega Buster |
Mega Ball |
Tornado Hold |
Thunder Claw |
Flash bomb |
Ice Wave |
Flame Sword |
Homing Sniper |
Astro Crush |
Water Balloon |
|---|---|---|---|---|---|---|---|---|---|---|
| Tengu Man | 2 – 4 | 1 | 1 | 1 | 1 | 5 | 2 | 1 | 0 | 1 |
| Clown Man | 1 – 3 | 1 | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 1 |
| Grenade Man | 1 – 3 | 1 | 1 | 4 | 2 | 1 | 1 | 1 | 0 | 1 |
| Frost Man | 1 – 3 | 1 | 1 | 1 | 3 | 0 | 3 | 0 | 0 | 0 |
| Sword Man | 1 – 3 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 4 |
| Search Man | 1 – 3 | 1 | 1 | 1 | 1 | 1 | 4 | 1 | 0 | 1 |
| Astro Man | 1 – 3 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 0 | 1 |
| Aqua Man | 1 – 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 8 | 0 |
| Intermission bosses | Mega Buster |
Mega Ball |
Tornado Hold |
Thunder Claw |
Flash bomb |
Ice Wave |
Flame Sword |
Homing Sniper |
Astro Crush |
Water Balloon |
|---|---|---|---|---|---|---|---|---|---|---|
| Cut Man | ||||||||||
| Duo | ||||||||||
| Wood Man |
| Skull Castle Bosses |
Mega Buster |
Mega Ball |
Tornado Hold |
Thunder Claw |
Flash bomb |
Ice Wave |
Flame Sword |
Homing Sniper |
Astro Crush |
Water Balloon |
|---|---|---|---|---|---|---|---|---|---|---|
| Owl boss | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Plane boss | 2 – 2 | 2 | 1 | 2 | 1 | 1 | 2 | 0 | 10 | 1 |
| Bass | 1 – 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 3 | 1 |
| Green Devil | 1 – 2 | 1 | 0 | 4 | 2 | 0 | 1 | 1 | 0 | 0 |
| Dr. Wily 1 | 1 – 2 | 2 | 1 | 1 | 1 | 1 | 2 | 0 | 6 | 3 |
| Dr. Wily 2 | 1 – 2 | 0 | 0 | 0 | 2 | 0 | 4 | 0 | 0 | 1 |