Vampire the Masquerade - Bloodlines is played using a mouse and a keyboard. The controls are quite simplistic, similar to most First-Person Shooter games, especially Half-Life, where the player targets his attack with the pointer at the center of the screen and commences the attack using solely the mouse.
Control
Action
Attack / Bring up Dialogue Subtitles.
Activate current Discipline.
W or ↑
Move forward.
S or ↓
Move backward.
←
turn left
→
turn right
A or ,
Move left (strafe)
D or .
Move right (strafe)
space
Jump
ctrl
Crouch
B or '
Swim up
V or /
Swim down
tab
change attack mode / toggle to alternative firing mode (while using a ranged weapon)