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Box artwork for Trauma Center: Under the Knife 2.
Box artwork for Trauma Center: Under the Knife 2.
Trauma Center: Under the Knife 2
Year released2008
System(s)Nintendo DS
Preceded byTrauma Center: New Blood
Followed byTrauma Team
SeriesTrauma Center
ModesSingle player
Rating(s)ESRB TeenCERO Ages 12 and up
LinksTrauma Center: Under the Knife 2 ChannelSearchSearch

Trauma Center: Under the Knife 2 (救急救命 カドゥケウス2 Kyūkyū Kyūmei Kadukeusu 2?, lit. "Medical Emergency: Caduceus 2") is a surgical simulation game developed for the Nintendo DS and the fourth in the Trauma Center series. The game is a sequel to Trauma Center: Under the Knife. The character designs of Under the Knife 2 were provided by Masayuki Doi, who worked on Trauma Center: Second Opinion, instead of Maguro Ikehata (who worked on the original Under the Knife).


Dr. Derek Stiles, the protagonist, and his nurse, Angie Thompson, travel to the African nation of Costigar to help out at one of their hospitals. While there, they begin to research a new fever, which becomes serious enough for Derek to use the Healing Touch on a patient. Soon after this, Derek and Angie are called back to the Caduceus headquarters, Derek’s medical organization, to investigate a new GUILT-related disease tentatively called Post-GUILT Syndrome.


The gameplay is much easier; The defibrillator are easy to use. The syringes don't have any lack. And the sutures don't need too much zigzag. Also, there is a special gadget to change the difficulty whenever the player play and the stages are arranged so the player can play it anytime they want. Trauma Center Under the Knife 2 really use the function of stylus, touch screen, and the microphone. There is a lot of tools to use; antibiotic gel, syringe, sutures/stitches, the drain, laser, ultrasound, scalpel, and the forceps. Also there is additional tools like bandages, defibrillator, air compressor, wire, and penlight. The player can also use the Healing Touch to slow the time.

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