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Challenges are a set of runs with prechosen characters and special conditions. This mode is unlocked by completing a successful run without resting once, and completing these runs will unlock further rewards.

Parole Violation[edit]

"You can't get caught again. You won't be able to save the world from behind the bars."

Challenge: ★★
Difficulty: True Believer
Character: Miku
Background: World of Horror
Old God: Random

You start this run with -10% Doom, but the effects of Miku's "Mayhem" status are disabled. Unlocks the Arm Sling item upon completion.

Going Cold Turkey[edit]

"I think I've chosen the worst time to quit..."

Challenge:
Difficulty: Cultist
Character: Haru
Background: World of Horror
Old God: Random

You start this run with the Bottle of Water item, but all Cigarettes obtained are automatically discarded. Unlocks the Brick weapon upon completion.

But Dad!!![edit]

"You're grounded for a week, young lady. Why won't you read some books for a change?"

Challenge: ★★
Difficulty: True Believer
Character: Moriko Ishii
Background: World of Horror
Old God: Random

You start this run with the Inspiring Novel item, but all firearms obtained are automatically discarded. Unlocks the Brain Worms spell upon completion.

Ghastly Presence[edit]

"Don't you see the person following me...?"

Challenge: ★★
Difficulty: Cultist
Character: Kirie Minami
Background: World of Horror
Old God: Random

You start this run with the Mind Drain spell and a random spell, but also have the "Ghastly Presence" status, which prevents all offensive actions. Unlocks the Insomnia status upon completion.

Ghost Town[edit]

"Only after your photo shoot was cancelled you discovered that every business in Shiokawa is closed. Did everyone move out or...?"

Challenge: ★★
Difficulty: Cultist
Character: Mizuki Hamasaki
Background: The Seventh Curse
Old God: Random

All additional actions except for resting are disabled. Unlocks the Swollen Joint injury upon completion.

Wrong Book![edit]

"I swear the covers were identical!"

Challenge:
Difficulty: True Believer
Character: Toshiaki Wakamatsu
Background: World of Horror
Old God: Random

Replaces Toshiaki's Necronomicon item with the Cook Book item, which has a 10% chance of giving you a random food item when investigating a location.

Mimi's Little Project[edit]

"It's time to put my knowledge to use..."

Challenge: ★★★
Difficulty: True Believer
Character: Mimi
Background: World of Horror
Old God: Random

Before starting a mystery, you must choose one of the following projects to perform on yourself (you do not have to do so when all mysteries are finished and you go to the Lighthouse):

  • Replace the liquid in your eyeball with a saline solution: -1 Perception, -10% chance to all combat actions
  • Stab an icepick through the nose to disable the pain receptors in your brain: -1 damage taken, -2 Knowledge
  • Forcibly rewire your vestibular system: -1 Luck, fail all event checks
  • Implant a second human heart: -1 Charisma, +5% Doom
  • Break your arm to form a new joint: -1 Strength, slower combat actions
  • Sell your kidney to finance your project: +1 Fund, -3 maximum Stamina
  • Cut off your kneecap: -2 Dexterity, -1 item slot
  • Graft bear claws to your toes: +2 Kick damage, gain a random injury upon beginning a mystery

Unlocks the Holy Glyph spell upon completion.