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All these items are used upon being picked up.
- Elemental Icons provide you with ammo for your weapons. You get +10 for and Icon, +40 for a Cube and +100 for a Tablet.
- Health Potions increase your current health. You gain +10 for a Vial, +30 for a Flask and +60 for a Bottle.
- Blood Rose gives you 100 health to a maximum of 250. If you don't have an Elder Plate, try to get as many health as possible with Health Potions before picking up a Blood Rose.
- Angel Charm makes you invulnerable. Difficult to obtain, but the effect lasts long enough to survive even the hardest of the battles. You can survive even falling into a bottomless pit, but you will die as soon as the effect wears off, so bottomless pits are still fatal even with this artifact.