| Robot master | Weapon | Trajectory | Effect | Buttons | Effective |
|---|---|---|---|---|---|
| Air Man | Air Shooter | arc upwards | - | - | Crash Man |
| Crash Man | Crash Bomber | (straight) | destroys some walls | - | Flash Man |
| Flash Man | Time Stopper | full screen | stuns all enemies | - | Quick Man |
| Quick Man | Quick Boomerang | boomerang | rapid fire | press and hold B | Metal Man |
| Metal Man | Metal Blade | multi-directional | - | press Up/Fwd/Down + B | Bubble Man |
| Bubble Man | Bubble Lead | along floor | - | - | Heat Man |
| Heat Man | Atomic Fire | (straight) | charge up | press and hold B | Wood Man |
| Wood Man | Leaf Shield | barrier & multi-directional | - | stand still and press B, then press any direction |
Air Man |
Air Shooter
The Air Shooter is acquired upon the defeat of Air Man. It fires three small tornadoes, which travel out from Mega Man's position and arc upward, eventually disappearing off the top of the screen.
Metal Blade
The Metal Blade is gained after defeating Metal Man. Using this, Mega Man can fire a circular saw blade in any of eight directions, simply by holding the desired direction of the D-Pad while firing. Firing the Metal Blade uses relatively little weapon energy. Because of its multidirectional capability and since it is effective against almost all of the game's enemies, the Metal Blade is a very useful, and over powered, weapon in Mega Man's arsenal.
Crash Bomber
The Crash Bomber fires a small bomb in a straight line from Mega Man's position. In addition to damaging enemies on contact, it will also attach itself to almost any surface and then explode a few seconds later. This weapon also makes a useful tool for reaching items and shortcuts which are blocked by special barriers in Flash Man's stage, Heat Man's stage and in Dr. Wily's Fortress.
Time Stopper
Acquired after defeating Flash Man, this is more of a tool than a weapon, as it effectively damages very few of Mega Man's enemies. Rather, Mega Man uses the Time Stopper to freeze all enemies on the screen, allowing him to simply avoid battling with them. Once the Time Stopper is activated, its time-freezing effect cannot be cancelled until the weapon's energy is completely exhausted.
Bubble Lead
Bubble Lead is affected by gravity and rolls along the ground until it contacts an enemy or an immovable barrier, or else falls off the screen. It is effective for attacking enemies which are below Mega Man, or which are too close to the ground to be easily targeted by other weapons.
Leaf Shield
The Leaf Shield is gained from Wood Man and can be used for defense or offense. When activated, it creates a circle of indestructible leaves which surround Mega Man. Enemies contacting the shield will sustain damage, but Mega Man must stand motionless or else the shield will fly away from his body. Once the shield is activated, simply pressing a direction on the D-Pad will cause the shield to fly in that direction, still damaging enemies as it goes. If Mega Man jumps, the Leaf Shield will travel directly upwards.
Quick Boomerang
Quick Boomerang rapidly fires boomerangs in a tight arc in front of Mega Man's position. The weapon effectively creates a wave of boomerangs in front of Mega Man. The boomerangs don't travel very far, but they can be effective for attacking enemies which are just above or below Mega Man's position.
Atomic Fire
This weapon is gained after Heat Man's defeat. The weapon can be charged by holding 
before releasing, which can result in three different-sized fireballs. The larger the fireball, the more weapon energy is used. Atomic fire has three forms: the first and weakest form is created by tapping the button that does little damage and uses little energy. The next form does moderate damage and uses a little more energy than the first form. The final form does the most damage and uses the most energy and it is also the largest form.