Devil May Cry 4/Bosses

Before we begin, there are a couple of rules you should know:

1. With Nero, when using your "buster" move against a boss, before using it, turn on devil trigger. Because of the animation used for the move, if you turn on devil trigger before you use buster, and when the animation starts turn it off, you use a more powerful buster move (as if you were in devil trigger) but do not drain your devil trigger.
2. When in a boss fight, or any fight for that matter. If you are in a hold where you cannot move or are taking constant damage for a prolonged period of time, turning on devil trigger provides about one second of invincibility where nothing hurts you, and you break out of an enemy's grasp
3. During any battle with Nero, always have the "gun" button held down to keep it charging. For that I suggest only for Nero to change the button configuration from (square), to R1 for the playstation, and if the configuration keeps the same aspect from X, to RT. Aswell as before any boss fight max out exceed by revving your sword or if you have master max act and have purchased it use that, although the exceed does not play a major part, it just allows a couple stronger hits in.

Dante Boss Fight

In either fight against Dante with Nero sure you could technically use a fair tactic, or you could you the easy way. With Nero against Dante you can just continually fire your gun (Blue Rose) then once you get close enough to him, buster. This technique may be a tad difficult to get used to, due to the distance you need to be away from him, you can't be too far away, but if you get too close he uses his stinger move.