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| Perks | Level | Description | |
|---|---|---|---|
| Action Boy | 16 | ||
| Adamantium Skeleton | 14 | 50% all damage taken by limbs | |
| Animal Friend | 10 | Animals don't attack you | |
| Better Criticals | 16 | Increases your chance of getting critical hits | |
| Bloody Mess | 6 | 5% more damage, enemies will explode, literally. | |
| Cannibal | 12 | Option to sacrifice Karma to eat human bodies to regain health | |
| Chem Resistant | 16 | 50% chance to become addicted to chems | |
| Chemist | 14 | Chems are 50% more effective | |
| Child at Heart | 5 | Increases dialogues with children | |
| Commando | 8 | Increases VATS accuracy when using rifles | |
| Comprehension | 4 | additional skill point with every book read | |
| Computer Whiz | 18 | extra attempt to re-hack any computer you were locked out of | |
| Concentrated Fire | 18 | increases VATS accuracy | |
| Contract Killer | 14 | When you kill a good character, you can sell their ears for profit and negative Karma | |
| Cyborg | 16 | Permanently increases armor by 10% as well as more poison/radiation resistant | |
| Daddy's Girl (boy) | 2 | 5 intellectual/medicine skill | |
| Demolition Expert | 6 | addition 20% damage dealt to enemies when you use explosives | |
| Educated | 4 | 3 extra skill points when you advance in a skill | |
| Entomologist | 4 | 50% damage dealt to radioactive insects | |
| Explorer | 20 | Every location of the map is revealed | |
| Fast Metabolism | 12 | 20% more health gained when you eat Stimpaks | |
| Finesse | 5 | Increases chance to get critical hits | |
| Fortune Finder | 16 | Increases chance to find Nuka-Cola caps found in containers | |
| Grim Reapers Sprint | 20 | If you successfully kill an opponent using VATS, all VATS points are restored imediately | |
| Gun Nut | 2 | 2 small gun and repair skills | |
| Gunslinger | 6 | VATS accuracy is significantly increased when using pistols | |
| Here and Now | 10 | Increases one skill | of your choice |
| Impartial Mediation | 8 | 50 to speech skills | |
| Infiltrator | 18 | Grants one more time to try and pick a broken lock | |
| Intense training | 2 | 1 to any s.p.e.c.i.a.l skill | |
| Iron Fist | 5 | 5 points to unarmed skill | |
| Lady Killer/Black Widow | 2 | 10% more damage to opposite sex | |
| Lead Belly | 6 | 50% less radiation when you drink from irradiated water | |
| Lawbringer | 14 | When you kill an evil character you may sell their finger for positive Karma and profit | |
| Lifegiver | 12 | 30 hitpoints | |
| Light Step | 14 | You can never set off enemy mines or traps | |
| Little League | 2 | 5 to melee damage | |
| Master Trader | 14 | every item you buy from NPC's is reduced by 25% | |
| Mister Sandman | 10 | Option to silently kill sleeping humans or ghouls | |
| Mysterious Stranger | 10 | Stranger with a magnum will randomly appear in VATS to help you out | |
| Nerd Rage! | 10 | Strength is increased to | 10 |
| Nightperson | 10 | 2 Intelligence and Perception when the sun is down | |
| Ninja | 20 | Sneak attacks do 25% more damage | |
| Paralyzing Palm | 18 | Chance to stun an enemy when using VATS unarmed | |
| Pyromaniac | 12 | 50% more damage when using flame based weapons | |
| Rad Resistance | 8 | 25% more radiation resistance | |
| Robotics Expert | 12 | 25% damage dealt to robots | |
| Scroundel | 4 | 4 speech/barter | s |
| Silent Running | 12 | 10 points to sneak skill and running when hidden doesn't affect being detected | |
| Size Matters | 8 | 5 points to Big Guns skill | |
| Sniper | 12 | When using VATS, chances to hit the head are significantly increased | |
| Solar Powered | 20 | When in the sun, you gain 2 points towards strenght and slowly regenerate health | |
| Strong Back | 8 | you can carry 50 pounds extra weight | |
| Swift Learner | 2 | 10% exp to each of your skills | |
| Tag! | 16 | instantly increases any skill by 10 | |
| Thief | 2 | 5 points to sneak/lock pick skills | |
| Toughness | 6 | 25% more damage resistant to melee attacks |